2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

Related Products

PDF 3.95 MB

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W016498R
    Paraxanthine (Standard)
    Paraxanthine (Standard) is the analytical standard of Paraxanthine. This product is intended for research and analytical applications. Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.
    Paraxanthine (Standard)
  • HY-126915
    CNK-6004
    CNK-6004 is a Montirelin hydrate (NS-3) (HY-19154) metabolite.
    CNK-6004
  • HY-W749636
    N-De-2,4-difluorobenzyl dolutegravir
    N-De-2,4-difluorobenzyl dolutegravir is a metabolite of Dolutegravir (HY-13238). Dolutegravir is a HIV integrase inhibitor inhibitor.
    N-De-2,4-difluorobenzyl dolutegravir
  • HY-137769R
    Captopril EP Impurity C (Standard)
    Captopril EP Impurity C (Standard) is the analytical standard of Captopril EP Impurity C. This product is intended for research and analytical applications. Captopril EP Impurity C is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM).
    Captopril EP Impurity C (Standard)
  • HY-W718316
    5,6-Chrysenedione
    5,6-Chrysenedione is the photochemical degradation product of 6-Aminochrysene (HY-108315).
    5,6-Chrysenedione
  • HY-137768R
    Captopril EP Impurity B (Standard)
    Captopril EP Impurity B (Standard) is the analytical standard of Captopril EP Impurity B. This product is intended for research and analytical applications. Captopril EP Impurity B is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM).
    Captopril EP Impurity B (Standard)
  • HY-118527
    Fenirofibrate
    Fenirofibrate (LF 2151), a metabolite of Fenofibrate (HY-17356), is an orally active fibrate, used in the study of hypertriglyceridemia.
    Fenirofibrate
  • HY-43670R
    Chlorthalidone impurity (Standard)
    Chlorthalidone impurity (Standard) is the analytical standard of Chlorthalidone impurity. This product is intended for research and analytical applications. Chlorthalidone impurity is a metabolite of Chlorthalidone (HY-15833). Chlorthalidone is a thiazide-like diuretic used to treat hypertension.
    Chlorthalidone impurity (Standard)
  • HY-124464
    MD 770222
    MD 770222, a major plasma O-demethyl metabolite of Cimoxatone (HY-15386), is an orally active, selective and reversible MAO A inhibitor. MD 770222 shows less potent than Cimoxatone.
    MD 770222
  • HY-124414AR
    4'-Hydroxytamoxifen TFA (Standard)
    4'-Hydroxytamoxifen (TFA) (Standard) is the analytical standard of 4'-Hydroxytamoxifen (TFA). This product is intended for research and analytical applications. 4'-Hydroxytamoxifen TFA is a salt form of a metabolite of Tamoxifen. 4'-Hydroxytamoxifen TFA has a higher affinity for ER than Tamoxifen. 4'-Hydroxytamoxifen TFA induces non-apoptotic cytotoxicity in human endometrial adenocarcinoma cells[1].
    4'-Hydroxytamoxifen TFA (Standard)
  • HY-100620R
    RPR121056 (Standard)
    RPR121056 (Standard) is the analytical standard of RPR121056. This product is intended for research and analytical applications. RPR121056 (APC) is a metabolite of Irinotecan (CPT-11), which is generated by CYP3A4. Irinotecan (CPT-11) is an antineoplastic agent that inhibits topoisomerase type I, causing cell death, and is widely used in the treatment of colorectal cancer. Irinotecan also directly inhibits AChE[1].
    RPR121056 (Standard)
  • HY-G0008AR
    O-Desmethyl Mebeverine alcohol hydrochloride (Standard)
    Diethyl phthalate (Standard) is the analytical standard of Diethyl phthalate. This product is intended for research and analytical applications. Diethyl phthalate is an endocrine disruptor that has the activity of affecting the apoptosis system of PC12 cells. Diethyl phthalate is widely used in a variety of plastics and personal care products. Diethyl phthalate has shown the potential to induce male reproductive toxicity unrelated to androgens in animal experiments.
    O-Desmethyl Mebeverine alcohol hydrochloride (Standard)
  • HY-W008772R
    4-Hydroxymephenytoin (Standard)
    4-Hydroxymephenytoin (Standard) is the analytical standard of 4-Hydroxymephenytoin. This product is intended for research and analytical applications. 4-Hydroxymephenytoin is a metabolism of an antiepileptic agent mephenytoin, which is used as a CYP2C19 substrate.
    4-Hydroxymephenytoin (Standard)
  • HY-15005B
    Sofosbuvir impurity C
    Sofosbuvir impurity C is an impurity of Sofosbuvir, Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
    Sofosbuvir impurity C
  • HY-I0727
    Sofosbuvir impurity E
    Sofosbuvir impurity E is an impurity of Sofosbuvir, Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
    Sofosbuvir impurity E
  • HY-I0719
    Sofosbuvir impurity B
    Sofosbuvir impurity B is an impurity of Sofosbuvir, Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
    Sofosbuvir impurity B
  • HY-I0723
    Sofosbuvir impurity D
    Sofosbuvir impurity D is an impurity of Sofosbuvir, Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
    Sofosbuvir impurity D
  • HY-U00199
    Norzopiclone
    Norzopiclone is the inactive metabolite of Zopiclone. Norzopiclone has some anxiolytic properties.
    Norzopiclone
Cat. No. Product Name / Synonyms Application Reactivity